Myasthenia Gravis
A progressive disorder(striated, skeletal muscles)
Muscle innervated by the cranial nerves(face, lips, tongue, neck, and throat)
Can cause weakness and fatigue
Exerted by exercise but usually improved by ant cholinesterase drugs
Pathophysiology
Patient blood cells and thymus produce antibodies
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Antibodies block and destroy or weaken neurotransmitter in
neuromuscular junction(esp. acH receptor)
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Failure in transmission of acH neurotransmitter to muscle
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Muscular weakness or paralysis
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