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"If I were an angel, I would be a fallen one

trying to fly on broken wings, with a broken heart.

That was when you found me and taught me to

fly again, because you loved me

stroke

STROKE

is the rapidly developing loss of brain function(s)

due to disturbance in the blood supply to the brain.

PATHOPYSIOLOGY

Group of neurons lose afferent stimulation

â

These neurons are hypersensitive and

easily activated

â

Fire abnormally

â

Seizure

increase ICP

Increase intracranial pressure

ICP more than 15 mmHg

Due to an á in any of the 3 components namely:

Brain-88%

CSF- 9%

Blood-3%

PATHOPYSIOLOGY

Trauma

â

Edema

â

áICP

â

Blood vessel compression

â

â Oxygen perfusion in the brain

â

Brain cell death

epilipsy

Epilepsy

Recurrent seizures

PATHOPYSIOLOGY

Group of neurons lose afferent stimulation

â

Become epileptogenic focus

∞these neurons are hypersensitivity and easily activated

â

Fire normally

â

Seizure

Amyotropic Lateral sclerosis

Amyotropic Lateral sclerosis

A progressive debilitating and fatal disease involving

 degeneration of motor neurons

²loss of voluntary muscle control

²mental status is intact and not affected

ALS results from degeneration of:

²upper motor neurons in the medulla oblongata

²lower motor neurons in the spinal cord

PATHOPYSIOLOGY

Motor neurons in medulla oblongata and spinal cord die

â

Muscle they serves atrophy (loss of muscle tone

â

Weakness/paralysis of the muscle

â

Signs and symptoms vary according to what neuron is

affected and what muscle they serves

multiple sclerosis

Multiple Sclerosis

A progressive demyelination of the white matter

of the brain and spinal cord

Characterized by exacerbations and remission

PATHOPYSIOLOGY

Infection/ autoimmune response

â
attack white matter of brain

â

Destruction of myelin sheath

â

Scarring (gliosis, hard yellow plaques)

â

Disruption of nerves conduction

â

Neurologic dysfunction